Enrichment, detection and clinical significance of circulating tumor cells.

@article{Arya2013EnrichmentDA,
  title={Enrichment, detection and clinical significance of circulating tumor cells.},
  author={Sunil K. Arya and Bing Lim and A. R. A. Rahman},
  journal={Lab on a chip},
  year={2013},
  volume={13 11},
  pages={1995-2027}
}
Circulating Tumor Cells (CTCs) are shed from primary or secondary tumors into blood circulation. Accessing and analyzing these cells provides a non-invasive alternative to tissue biopsy. CTCs are estimated to be as few as 1 cell among a few million WBCs and few billion RBCs in 1 ml of patient blood and are rarely found in healthy individuals. CTCs are FDA approved for prognosis of the major cancers, namely, Breast, Colon and Prostate. Currently, more than 400 clinical trials are ongoing to… CONTINUE READING