Enriching the molecular definition of the airway "field of cancerization:" establishing new paradigms for the patient at risk for lung cancer.

@article{Gomperts2013EnrichingTM,
  title={Enriching the molecular definition of the airway "field of cancerization:" establishing new paradigms for the patient at risk for lung cancer.},
  author={Brigitte Gomperts and Tonya C. Walser and Avrum Spira and Steven Dubinett},
  journal={Cancer prevention research},
  year={2013},
  volume={6 1},
  pages={
          4-7
        }
}
The "field of cancerization" refers to histologically normal-appearing tissue adjacent to neoplastic tissue that displays molecular abnormalities, some of which are the same as those of the tumor. Improving our understanding of these molecular events is likely to increase our understanding of carcinogenesis. Kadara and colleagues attempt to characterize the molecular events occurring temporally and spatially within the field of cancerization of patients with early-stage non-small cell lung… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 12 CITATIONS

Early Events in the Molecular Pathogenesis of Lung Cancer.

  • Cancer prevention research
  • 2016
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Decreased Interferon Alpha/Beta Signature Associated with Human Lung Tumorigenesis.

  • Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
  • 2015