Enlisting Genomics to Understand Flu Evolution

  title={Enlisting Genomics to Understand Flu Evolution},
  journal={PLoS Biology},
  • Published in PLoS Biology 2005
1512 normal enzyme. Then, they replaced the oxygen in question with a sulfur atom. The reaction didn’t work as well because, by the rules of chemistry, sulfur doesn’t like to bind to magnesium. But sulfur does like manganese and cadmium ions. So they replaced the magnesium with one of these other metal ions and measured the reaction. The researchers saw that these other metal ions restored (or “rescued”) enzymatic activity. In short, the enzyme needs a bond where the oxygen and the magnesium… CONTINUE READING

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