Enlargement of the receptive field size to low intensity mechanical stimulation in the rat spinal nerve ligation model of neuropathy.

@article{Suzuki2000EnlargementOT,
  title={Enlargement of the receptive field size to low intensity mechanical stimulation in the rat spinal nerve ligation model of neuropathy.},
  author={Rie Suzuki and Vesa K Kontinen and Elizabeth A. Matthews and Erika K. Williams and Anthony Henry Dickenson},
  journal={Experimental neurology},
  year={2000},
  volume={163 2},
  pages={408-13}
}
One characteristic of plasticity after peripheral tissue or nerve damage is receptive field reorganization, and enlargement of receptive field size has been suggested to occur in certain models of neuropathic pain. The aim of the present study was to explore whether enlargement of neuronal receptive fields could contribute to the mechanical allodynia found on the ipsilateral paw in the spinal nerve ligation model of neuropathy. After ligation of L(5)-L(6) spinal nerves, all rats developed… CONTINUE READING