Enlarged cisterna magna and the Dandy-Walker malformation: factors associated with chromosome abnormalities.

@article{Nyberg1991EnlargedCM,
  title={Enlarged cisterna magna and the Dandy-Walker malformation: factors associated with chromosome abnormalities.},
  author={David A. Nyberg and Barry S Mahony and F N Hegge and D E Hickok and David Luthy and Raj Kapur},
  journal={Obstetrics and gynecology},
  year={1991},
  volume={77 3},
  pages={436-42}
}
Thirty-three fetuses with an enlarged cisterna magna (10 mm or more) were evaluated to determine factors that might be associated with an underlying chromosome abnormality. Eighteen fetuses (55%) proved to have a chromosome abnormality, including trisomy 18 or trisomy 18 variant (12), trisomy 13 (three), Turner syndrome (one), or other rearrangements (two). Among various risk factors analyzed, the absence of ventricular dilatation correlated most strongly with a chromosome abnormality… CONTINUE READING

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