Enho Mutations Causing Low Adropin: A Possible Pathomechanism of MPO-ANCA Associated Lung Injury

@inproceedings{Gao2016EnhoMC,
  title={Enho Mutations Causing Low Adropin: A Possible Pathomechanism of MPO-ANCA Associated Lung Injury},
  author={Feng Gao and Jun Fang and Falin Chen and Chengdang Wang and Shu Mi Chen and Sheng Zhang and Xiaoting Lv and Jinchi Zhang and Qingliang He and Shaohuang Weng and Qicai Liu and Xinhua Lin},
  booktitle={EBioMedicine},
  year={2016}
}
BACKGROUND Myeloperoxidase (MPO) anti-neutrophil cytoplasm autoantibody (ANCA)-associated vasculitis commonly causes life-threatening pulmonary alveolar hemorrhage or fibrosis. Only a limited number of candidate gene variants have been explored, but hitherto, are not widely confirmed. In the present study, we investigated the importance of energy homeostasis associated gene (Enho) mutations and adropin deficiency in the development of MPO-ANCA associated lung injury. METHODS We analyzed the… CONTINUE READING
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