Enhancing the stability and biological functionalities of quantum dots via compact multifunctional ligands.

@article{Susumu2007EnhancingTS,
  title={Enhancing the stability and biological functionalities of quantum dots via compact multifunctional ligands.},
  author={Kimihiro Susumu and H. Tetsuo Uyeda and Igor L. Medintz and Thomas Pons and James B. Delehanty and Hedi Mattoussi},
  journal={Journal of the American Chemical Society},
  year={2007},
  volume={129 45},
  pages={13987-96}
}
We have designed and synthesized a series of modular ligands based on poly(ethylene glycol) (PEG) coupled with functional terminal groups to promote water-solubility and biocompatibility of quantum dots (QDs). Each ligand is comprised of three modules: a PEG single chain to promote hydrophilicity, a dihydrolipoic acid (DHLA) unit connected to one end of the PEG chain for strong anchoring onto the QD surface, and a potential biological functional group (biotin, carboxyl, and amine) at the other… CONTINUE READING
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