Enhancing the biological performance of synthetic polymeric materials by decoration with engineered, decellularized extracellular matrix.

@article{Sadr2012EnhancingTB,
  title={Enhancing the biological performance of synthetic polymeric materials by decoration with engineered, decellularized extracellular matrix.},
  author={Nasser Sadr and Benjamin E. Pippenger and Arnaud Scherberich and David Wendt and S. Mantero and Ivan Martin and Adam Papadimitropoulos},
  journal={Biomaterials},
  year={2012},
  volume={33 20},
  pages={5085-93}
}
Materials based on synthetic polymers can be extensively tailored in their physical properties but often suffer from limited biological functionality. Here we tested the hypothesis that the biological performance of 3D synthetic polymer-based scaffolds can be enhanced by extracellular matrix (ECM) deposited by cells in vitro and subsequently decellularized… CONTINUE READING