Enhancing the Sensitivity of Label-Free Silicon Photonic Biosensors through Increased Probe Molecule Density

@inproceedings{Hu2014EnhancingTS,
  title={Enhancing the Sensitivity of Label-Free Silicon Photonic Biosensors through Increased Probe Molecule Density},
  author={Shuren Hu and Yiliang Zhao and Kun Qin and Scott T. Retterer and Ivan I Kravchenko and Sharon M. Weiss},
  year={2014}
}
  • Shuren Hu, Yiliang Zhao, +3 authors Sharon M. Weiss
  • Published 2014
  • Physics
  • We report a greater than 5-fold increase in the detection sensitivity and a greater than 3-fold reduction in the response time of planar silicon photonic biosensors by increasing the density of probe molecules through the use of an in situ probe synthesis approach. DNA probe molecules are grown in a base-by-base manner with the desired sequence on silicon ring resonator and photonic crystal biosensors, resulting in a greater than 5-fold increase in surface area coverage compared to traditional… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 18 CITATIONS

    Graphene Sensor Based on Surface Plasmon Resonance for Optical Scanning

    VIEW 1 EXCERPT
    CITES BACKGROUND

    Optofluidic microcapillary biosensor for label-free, low glucose concentration detection.

    VIEW 1 EXCERPT
    CITES BACKGROUND

    Porous silicon sensors: From on-chip to mobile diagnostics

    VIEW 1 EXCERPT
    CITES METHODS

    Silicon Photonic Biochemical Sensor on Chip Based on Interferometry and Phase-Generated-Carrier Demodulation

    VIEW 1 EXCERPT
    CITES METHODS