Health sciences librarians frequently need to locate specific current information when providing reference service to clients. Over the years, reference librarians have devised various methods to help them quickly locate the correct title when needed. In the past, a separate card file, arranged by subject, containing records for reference monographs, helped the staff at the University of Minnesota Bio-Medical Library locate reference titles. The change to an online catalog provided new opportunities, enabling the staff to explore means to improve access to the reference collection and to also dispense with the onerous routine of producing and filing cards for that collection. While considering ways to increase access to the reference collection, correspondence on the Public Access Computer Systems Listserv called attention to the merits of increasing subject retrieval by enhancing bibliographic records with content information. The authors decided to undertake a project to enhance the approximately 1,000 titles in the reference collection at the University of Minnesota Bio-Medical Library.