Enhancing kidney function with thrombolytic therapy following donation after cardiac death: a multicenter quasi-blinded prospective randomized trial.

@article{Woodside2015EnhancingKF,
  title={Enhancing kidney function with thrombolytic therapy following donation after cardiac death: a multicenter quasi-blinded prospective randomized trial.},
  author={Kenneth J Woodside and David A. Goldfarb and John C Rabets and Edmund Q. Sanchez and Daniel J. Lebovitz and James A. Schulak and John J. Fung and Bijan Eghtesad},
  journal={Clinical transplantation},
  year={2015},
  volume={29 12},
  pages={1173-80}
}
Kidneys from donors after cardiac death (DCD) are at risk for inferior outcomes, possibly due to microthrombi and additional warm ischemia. We describe an organ procurement organization-wide trial utilizing thrombolytic tissue plasminogen activator (tPA) during machine pulsatile perfusion (MPP). A kidney from each recovered kidney pair was prospectively… CONTINUE READING