Enhancing influence of intranasal interleukin‐6 on slowwave activity and memory consolidation during sleep

@article{Benedict2009EnhancingIO,
  title={Enhancing influence of intranasal interleukin‐6 on slowwave activity and memory consolidation during sleep},
  author={Christian Benedict and J. Scheller and S. Rose-John and J. Born and L. Marshall},
  journal={The FASEB Journal},
  year={2009},
  volume={23},
  pages={3629 - 3636}
}
  • Christian Benedict, J. Scheller, +2 authors L. Marshall
  • Published 2009
  • Medicine
  • The FASEB Journal
    • The cytokine IL‐6 has been considered to exert neuromodulating influences on the brain, with promoting influences on sleep. Sleep enhances the consolidation of memories, and, in particular, late nocturnal sleep also represents a period of enhanced IL‐6 signaling, due to a distinctly enhanced availability of soluble IL‐6 receptors during this period, enabling trans‐signaling of IL‐6 to neurons. Thus, a contribution of IL‐6 to sleep‐dependent memory consolidation is hypothesized. To test this… CONTINUE READING
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    References

    SHOWING 1-10 OF 55 REFERENCES
    Interleukin‐6: a cytokine to forget
    • 242
    • PDF
    Sleep enhances IL‐6 trans‐signaling in humans
    • S. Dimitrov, T. Lange, +5 authors J. Born
    • Biology, Medicine
    • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
    • 2006
    • 84
    Effects of Cortisol Suppression on Sleep-Associated Consolidation of Neutral and Emotional Memory
    • 108
    Humoral Links between Sleep and the Immune System
    • 135
    Soluble interleukin‐6 (IL‐6) receptor augments central effects of IL‐6 in vivo
    • B. Schöbitz, G. Pezeshki, +4 authors J. M. Reul
    • Biology, Medicine
    • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
    • 1995
    • 145
    Acute effects of recombinant human interleukin-6 on endocrine and central nervous sleep functions in healthy men.
    • 387
    • PDF
    Brain-immune interactions in sleep.
    • 84
    IL-6 and Its Circadian Secretion in Humans
    • 270
    Learning-Dependent Increases in Sleep Spindle Density
    • 682
    • PDF
    Emotional memory formation is enhanced across sleep intervals with high amounts of rapid eye movement sleep.
    • 499
    • PDF