Enhancing influence of intranasal interleukin‐6 on slowwave activity and memory consolidation during sleep
@article{Benedict2009EnhancingIO, title={Enhancing influence of intranasal interleukin‐6 on slowwave activity and memory consolidation during sleep}, author={Christian Benedict and J. Scheller and S. Rose-John and J. Born and L. Marshall}, journal={The FASEB Journal}, year={2009}, volume={23}, pages={3629 - 3636} }
The cytokine IL‐6 has been considered to exert neuromodulating influences on the brain, with promoting influences on sleep. Sleep enhances the consolidation of memories, and, in particular, late nocturnal sleep also represents a period of enhanced IL‐6 signaling, due to a distinctly enhanced availability of soluble IL‐6 receptors during this period, enabling trans‐signaling of IL‐6 to neurons. Thus, a contribution of IL‐6 to sleep‐dependent memory consolidation is hypothesized. To test this… CONTINUE READING
Topics from this paper
Paper Mentions
71 Citations
Sleep smart—optimizing sleep for declarative learning and memory
- Psychology, Medicine
- Front. Psychol.
- 2015
- 55
- PDF
Sleep-dependent enhancement of emotional memory in early childhood
- Psychology, Medicine
- Scientific Reports
- 2018
- 6
A Role for Central Nervous Growth Hormone-Releasing Hormone Signaling in the Consolidation of Declarative Memories
- Biology, Medicine
- PloS one
- 2011
- 7
- PDF
Peripheral and central blockade of interleukin-6 trans-signaling differentially affects sleep architecture
- Psychology, Medicine
- Brain, Behavior, and Immunity
- 2015
- 20
The role of sleep and sleep deprivation in consolidating fear memories
- Psychology, Computer Science
- NeuroImage
- 2013
- 106
Can Slow-Wave Sleep Enhancement Improve Memory? A Review of Current Approaches and Cognitive Outcomes
- Psychology, Medicine
- The Yale journal of biology and medicine
- 2019
- 15
Interactive effects of stress reactivity and rapid eye movement sleep theta activity on emotional memory formation.
- Psychology, Medicine
- Hippocampus
- 2019
- 8
Slow oscillation-spindle coupling impairs emotional memory consolidation following stress
- Psychology, Biology
- 2020
- PDF
Inflammatory markers are associated with inhibitory avoidance memory deficit induced by sleep deprivation in rats
- Psychology, Medicine
- Behavioural Brain Research
- 2011
- 11
The role of interleukin-6 signaling in nervous tissue.
- Biology, Medicine
- Biochimica et biophysica acta
- 2016
- 138
- PDF
References
SHOWING 1-10 OF 55 REFERENCES
Interleukin‐6: a cytokine to forget
- Medicine, Biology
- FASEB journal : official publication of the Federation of American Societies for Experimental Biology
- 2004
- 242
- PDF
Sleep enhances IL‐6 trans‐signaling in humans
- Biology, Medicine
- FASEB journal : official publication of the Federation of American Societies for Experimental Biology
- 2006
- 84
Effects of Cortisol Suppression on Sleep-Associated Consolidation of Neutral and Emotional Memory
- Psychology, Medicine
- Biological Psychiatry
- 2005
- 108
Humoral Links between Sleep and the Immune System
- Biology, Medicine
- Annals of the New York Academy of Sciences
- 2003
- 135
Soluble interleukin‐6 (IL‐6) receptor augments central effects of IL‐6 in vivo
- Biology, Medicine
- FASEB journal : official publication of the Federation of American Societies for Experimental Biology
- 1995
- 145
Acute effects of recombinant human interleukin-6 on endocrine and central nervous sleep functions in healthy men.
- Medicine
- The Journal of clinical endocrinology and metabolism
- 1998
- 387
- PDF
Learning-Dependent Increases in Sleep Spindle Density
- Psychology, Medicine
- The Journal of Neuroscience
- 2002
- 682
- PDF
Emotional memory formation is enhanced across sleep intervals with high amounts of rapid eye movement sleep.
- Psychology, Medicine
- Learning & memory
- 2001
- 499
- PDF