Enhancing influence of intranasal interleukin‐6 on slowwave activity and memory consolidation during sleep

@article{Benedict2009EnhancingIO,
  title={Enhancing influence of intranasal interleukin‐6 on slowwave activity and memory consolidation during sleep},
  author={Christian Benedict and J. Scheller and S. Rose-John and J. Born and L. Marshall},
  journal={The FASEB Journal},
  year={2009},
  volume={23},
  pages={3629 - 3636}
}
  • Christian Benedict, J. Scheller, +2 authors L. Marshall
  • Published 2009
  • Medicine
  • The FASEB Journal
  • The cytokine IL‐6 has been considered to exert neuromodulating influences on the brain, with promoting influences on sleep. Sleep enhances the consolidation of memories, and, in particular, late nocturnal sleep also represents a period of enhanced IL‐6 signaling, due to a distinctly enhanced availability of soluble IL‐6 receptors during this period, enabling trans‐signaling of IL‐6 to neurons. Thus, a contribution of IL‐6 to sleep‐dependent memory consolidation is hypothesized. To test this… CONTINUE READING
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