Enhancing image quality in cleared tissue with adaptive optics.


Our ability to see fine detail at depth in tissues is limited by scattering and other refractive characteristics of the tissue. For fixed tissue, we can limit scattering with a variety of clearing protocols. This allows us to see deeper but not necessarily clearer. Refractive aberrations caused by the bulk index of refraction of the tissue and its… (More)
DOI: 10.1117/1.JBO.21.12.121508


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