• Corpus ID: 41423172

Enhancing effects of alpha-,beta-monoglycosylceramides on natural killer cell activity.

  title={Enhancing effects of alpha-,beta-monoglycosylceramides on natural killer cell activity.},
  author={Eiichi Kobayashi and Kazuhiro Motoki and Yasunori Yamaguchi and Takeshi Uchida and H. Fukushima and Y. Koezuka},
  journal={Bioorganic \& medicinal chemistry},
  volume={4 4},
We examined the in vitro and in vivo natural killer (NK) cell activity enhancing effects of alpha-, beta-galactosylceramide (GalCer) and alpha-, beta-glucosylceramide (GluCer) which have the same ceramide moiety, and of other alpha-, beta-GalCer having a different ceramide portion, and found that alpha-types show stronger enhancing effects than beta-types and the alpha-GalCer possesses the most potent activity among GalCers and GluCers having the same ceramide moiety. When the comparison of… 
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