Enhancing apoptotic cell clearance mitigates bacterial translocation and promotes tissue repair after gut ischemia-reperfusion injury

@inproceedings{Wu2012EnhancingAC,
  title={Enhancing apoptotic cell clearance mitigates bacterial translocation and promotes tissue repair after gut ischemia-reperfusion injury},
  author={Rongqian Wu and Weifeng Dong and Zhimin Wang and Asha Jacob and Tianpen Cui and Ping Wang},
  booktitle={International journal of molecular medicine},
  year={2012}
}
A key aspect of intestinal ischemia/reperfusion (I/R) injury is the increased occurrence of apoptotic cell death in the gut. Insufficient clearance of apoptotic cells leads to increased inflammation and impaired tissue repair. Our recent studies have shown that administration of milk fat globule-epidermal growth factor-factor 8 (MFG-E8), a crucial molecule for apoptotic cell clearance, reduces apoptosis and inflammation under various disease conditions. The purpose of this study was to… CONTINUE READING
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