Enhancing adoptive cancer immunotherapy with Vγ2Vδ2 T cells through pulse zoledronate stimulation

@inproceedings{Nada2017EnhancingAC,
  title={Enhancing adoptive cancer immunotherapy with Vγ2Vδ2 T cells through pulse zoledronate stimulation},
  author={Mohanad H. Nada and Hong Wang and Grefachew Workalemahu and Yoshimasa Tanaka and Craig T. Morita},
  booktitle={Journal for immunotherapy of cancer},
  year={2017}
}
BACKGROUND Human γδ T cells expressing Vγ2Vδ2 T cell receptors monitor foreign- and self-prenyl pyrophosphate metabolites in isoprenoid biosynthesis to mediate immunity to microbes and tumors. Adoptive immunotherapy with Vγ2Vδ2 T cells has been used to treat cancer patients with partial and complete remissions. Most clinical trials and preclinical studies… CONTINUE READING