Enhancing Surgical Vision by Using Real-Time Imaging of αvβ3-Integrin Targeted Near-Infrared Fluorescent Agent

@article{Themelis2011EnhancingSV,
  title={Enhancing Surgical Vision by Using Real-Time Imaging of αvβ3-Integrin Targeted Near-Infrared Fluorescent Agent},
  author={George Themelis and Niels J. Harlaar and Wendy Kelder and Joost Bart and Athanasios Sarantopoulos MSc and Gooitzen M. van Dam and PhD Vasilis Ntziachristos MSc},
  journal={Annals of Surgical Oncology},
  year={2011},
  volume={18},
  pages={3506-3513}
}
This study was designed to improve the surgical procedure and outcome of cancer surgery by means of real-time molecular imaging feedback of tumor spread and margin delineation using targeted near-infrared fluorescent probes with specificity to tumor biomarkers. Surgical excision of cancer often is confronted with difficulties in the identification of cancer spread and the accurate delineation of tumor margins. Currently, the assessment of tumor borders is afforded by postoperative pathology or… CONTINUE READING