Enhancing Oral Vaccine Potency by Targeting Intestinal M Cells

  title={Enhancing Oral Vaccine Potency by Targeting Intestinal M Cells},
  author={Ali Azizi and Ashok Kumar and Francisco Diaz-Mitoma and Jiri F. Mestecky},
  booktitle={PLoS pathogens},
The immune system in the gastrointestinal tract plays a crucial role in the control of infection, as it constitutes the first line of defense against mucosal pathogens. The attractive features of oral immunization have led to the exploration of a variety of oral delivery systems. However, none of these oral delivery systems have been applied to existing commercial vaccines. To overcome this, a new generation of oral vaccine delivery systems that target antigens to gut-associated lymphoid tissue… CONTINUE READING


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