Enhancing Cancer Drug Discovery through Novel Cell Signaling Pathway Panel Strategy

@inproceedings{Schweizer2013EnhancingCD,
  title={Enhancing Cancer Drug Discovery through Novel Cell Signaling Pathway Panel Strategy},
  author={Liang Schweizer and Litao Zhang},
  booktitle={Cancer growth and metastasis},
  year={2013}
}
The link between signaling pathways and diseases suggests the importance of pathway analysis for drug discovery. This includes target identification and validation, compound mode of action and drug candidate optimization. Here, we propose to apply cell signaling pathway panel approaches for oncology drug discovery. The strategies and guiding principles of the pathway panel approach are discussed. 2 pathway analysis examples with related processes and technology platforms are illustrated to… CONTINUE READING

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Building the Bridge from Drug Discovery to Clinical Research Using Pathway Approaches

  • L Zhang, L. Schweizer
  • Int Drug Discov
  • 2011

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