Enhancer of zeste acts as a major developmental regulator of Ciona intestinalis embryogenesis

@inproceedings{Goff2015EnhancerOZ,
  title={Enhancer of zeste acts as a major developmental regulator of Ciona intestinalis embryogenesis},
  author={Emilie Le Goff and Camille Martinand-Mari and Marianne Martin and J{\'e}r{\^o}me Feuillard and Yvan Boublik and Nelly Godefroy and Paul H. Mangeat and Stephen Baghdiguian and Giacomo Cavalli},
  booktitle={Biology open},
  year={2015}
}
The paradigm of developmental regulation by Polycomb group (PcG) proteins posits that they maintain silencing outside the spatial expression domains of their target genes, particularly of Hox genes, starting from mid embryogenesis. The Enhancer of zeste [E(z)] PcG protein is the catalytic subunit of the PRC2 complex, which silences its targets via… CONTINUE READING