Enhancer blocking and transvection at the Drosophila apterous locus.

@article{Gohl2008EnhancerBA,
  title={Enhancer blocking and transvection at the Drosophila apterous locus.},
  author={Daryl Gohl and Martin Mueller and Vincenzo Pirrotta and Markus Affolter and Paul Schedl},
  journal={Genetics},
  year={2008},
  volume={178 1},
  pages={127-43}
}
Intra- and interchromosomal interactions have been implicated in a number of genetic phenomena in diverse organisms, suggesting that the higher-order structural organization of chromosomes in the nucleus can have a profound impact on gene regulation. In Drosophila, homologous chromosomes remain paired in somatic tissues, allowing for trans interactions between genes and regulatory elements on the two homologs. One consequence of homolog pairing is the phenomenon of transvection, in which… CONTINUE READING

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