Enhancer action in trans is permitted throughout the Drosophila genome.

@article{Chen2002EnhancerAI,
  title={Enhancer action in trans is permitted throughout the Drosophila genome.},
  author={Ji-long Chen and Kathryn L. Huisinga and Michaela M Viering and Sharon A Ou and Chao-Ting Wu and Pamela K Geyer},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2002},
  volume={99 6},
  pages={3723-8}
}
Interactions between paired homologous genes can lead to changes in gene expression. Such trans-regulatory effects exemplify transvection and are displayed by many genes in Drosophila, in which homologous chromosomes are paired somatically. Transvection involving the yellow cuticle pigmentation gene can occur by at least two mechanisms, one involving the trans-action of enhancers on a paired promoter and a second involving pairing-mediated bypass of a chromatin insulator. A system was developed… CONTINUE READING

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