Enhancement of tyrosyl phosphorylation and protein expression of eps8 by v-Src.

@article{Maa1999EnhancementOT,
  title={Enhancement of tyrosyl phosphorylation and protein expression of eps8 by v-Src.},
  author={M C Maa and Jonathan R. Lai and Ro-Ting Lin and T H Leu},
  journal={Biochimica et biophysica acta},
  year={1999},
  volume={1450 3},
  pages={341-51}
}
Two eps8 isoforms, p97eps8 and p68eps8, were previously identified as substrates for receptor tyrosine kinases. Analysis of eps8 phosphotyrosine content in v-Src transformed cells (IV5) revealed that both isoforms were highly tyrosyl phosphorylated and their readiness to be phosphorylated by Src in vitro further indicated that they were putative Src substrates as well. Indeed, the enhancement of tyrosyl phosphorylation of p97eps8 detected in cells coexpressing both p97eps8 and active Src… CONTINUE READING

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