Enhancement of tumor growth in mice: evidence for the involvement of host macrophages.

  title={Enhancement of tumor growth in mice: evidence for the involvement of host macrophages.},
  author={Salam Kadhim and Robert C. Rees},
  journal={Cellular immunology},
  volume={87 1},
Intratumor host cells of methylcholanthrene-induced fibrosarcoma(s) were shown to enhance the in vivo outgrowth of syngeneic homologous tumors (MC1A, Mc2A, Mc2B) but not two heterologous T-lymphomas (EL4 and TLX9) in the Winn adoptive transfer assay. This enhancing activity was not restricted only to the latent period of tumor growth but was also observed during the period of active in vivo tumor proliferation. Tumor enhancement was mediated by a population of cells adherent to nylon wool and… CONTINUE READING
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