Enhancement of the lipid content and physical properties of gastric mucus by geranylgeranylacetone.

@article{Bilski1987EnhancementOT,
  title={Enhancement of the lipid content and physical properties of gastric mucus by geranylgeranylacetone.},
  author={Jan Bilski and Jerzy Sarosiek and Varahabhotla L.N. Murty and Mitsuru Aono and Motoyuki Moriga and Amalia Slomiany and Bronislaw L. Slomiany},
  journal={Biochemical pharmacology},
  year={1987},
  volume={36 23},
  pages={
          4059-65
        }
}
The effects of intragastric administration of geranylgeranylacetone (GGA) on the content, composition and physical properties of the mucus component of the gastric mucosal barrier were investigated. One group of rats received twice daily for 3 consecutive days a dose of 100 mg/kg body weight of GGA, while the control group was subjected to daily doses of the vehicle. Sixteen hours following the last dose, the animals were killed, and their stomach was cut open and subjected to measurements of… CONTINUE READING
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