Enhancement of the inducible NO synthase activation by retinoic acid is mimicked by RARalpha agonist in vivo.

Abstract

We have previously shown that all-trans retinoic acid (atRA), the active metabolite of vitamin A, enhances the activation of the inducible nitric oxide synthase (NOS II) pathway, a component of innate immunity, in rats in vivo. We investigated the relative contribution of retinoic acid receptor-alpha (RARalpha) and retinoid X receptors (RXRs) to NOS II… (More)

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@article{SeguinDevaux2002EnhancementOT, title={Enhancement of the inducible NO synthase activation by retinoic acid is mimicked by RARalpha agonist in vivo.}, author={Carole Seguin-Devaux and Yvan Devaux and V{\'e}ronique Latger-Cannard and Sandrine A Grosjean and C{\'e}cile Rochette-Egly and Fa{\"{i}ez Zannad and Claude Meistelman and Paul Michel Mertes and Dan Longrois}, journal={American journal of physiology. Endocrinology and metabolism}, year={2002}, volume={283 3}, pages={E525-35} }