Enhancement of scopolamine production in Hyoscyamus muticus L. hairy root cultures by genetic engineering

Abstract

 In order to test the possibility of enhancing the production of pharmaceutically valuable scopolamine in transgenic cultures, the 35S-h6h transgene that codes for the enzyme hyoscyamine-6β-hydroxylase (EC 1.14.11.11) was introduced into Hyoscyamus muticus L. strain Cairo (Egyptian henbane). This plant was chosen for its capability to produce very high… (More)
DOI: 10.1007/s004250050592

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