Enhancement of repopulation and hematopoiesis of bone marrow cells in irradiated mice by oral administration of PG101, a water-soluble extract from Lentinus lepideus.

@article{Jin2003EnhancementOR,
  title={Enhancement of repopulation and hematopoiesis of bone marrow cells in irradiated mice by oral administration of PG101, a water-soluble extract from Lentinus lepideus.},
  author={Mirim Jin and Hyang Jeon and Hyung Jin Jung and Bongcheol Kim and Sung Seup Shin and Jeong June Choi and Jong Kyu Lee and Chang-Yuil Kang and Sunyoung Kim},
  journal={Experimental biology and medicine},
  year={2003},
  volume={228 6},
  pages={759-66}
}
PG101 is a water-soluble extract from Lentinus lepideus. It is a potential biological response modifier that activates selective cytokines in vitro, mainly by controlling cellular transcription factor NF-kappaB. Effects of PG101 were tested on bone marrow cells in irradiated mice. Mice were irradiated with a dose of 6 Gy and were given PG101 by gavages daily for 24 days. In PG101-treated mice, the number of colony-forming cells, including colony-forming units (CFU)-granulocytes/macrophages (GM… CONTINUE READING
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