Enhancement of particle deposition by flow-limiting segments in humans.

@article{Smaldone1985EnhancementOP,
  title={Enhancement of particle deposition by flow-limiting segments in humans.},
  author={Gerald C. Smaldone and M S Messina},
  journal={Journal of applied physiology},
  year={1985},
  volume={59 2},
  pages={509-14}
}
Severe chronic obstructive pulmonary disease is associated with central deposition of inhaled aerosols. This pattern may be due to functional narrowing of the large airways during expiration at flow-limiting segments (FLS). Using a gamma camera and 2.5-micron particles, we compared the pattern of aerosol deposition following quiet breathing with that after… CONTINUE READING