Enhancement of ouabain and calcium ionophore A23187 of outward transport of polyamines from lymphocytes.

Abstract

Human lymphocytes in culture loaded with radioactive polyamines slowly release radioactivity into the medium. N1-Acetylspermidine is mostly released from spermidine and spermine. Both ouabain and calcium ionophore A23187 increase the outward transport, but by different mechanisms. Ouabain inhibits the acetylation of spermidine, and free spermidine is… (More)

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@article{Fulgosi1991EnhancementOO, title={Enhancement of ouabain and calcium ionophore A23187 of outward transport of polyamines from lymphocytes.}, author={B Fulgosi and Sebastiano Colombatto and Maria Angelica Grillo}, journal={Biological chemistry Hoppe-Seyler}, year={1991}, volume={372 2}, pages={79-82} }