Enhancement of offset analgesia during sequential testing.

  title={Enhancement of offset analgesia during sequential testing.},
  author={Stuart W. G. Derbyshire and J. Osborn},
  journal={European journal of pain},
  volume={12 8},
Interruption of a continuous noxious heat by a relatively greater noxious heat evokes reductions in pain experience when the original noxious heat returns. The reduction is greater than that evoked by continuous delivery of noxious heat. This disproportionate reduction in pain experience, known as offset analgesia, is presumably mediated by a mechanism different to adaptation or habituation. Reduction in pain experience to an equivalent noxious stimulus, however, has also been demonstrated when… CONTINUE READING

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