Enhancement of neutrophil-mediated killing of Plasmodium falciparum asexual blood forms by fatty acids: importance of fatty acid structure.

@article{Kumaratilake1997EnhancementON,
  title={Enhancement of neutrophil-mediated killing of Plasmodium falciparum asexual blood forms by fatty acids: importance of fatty acid structure.},
  author={L. M. Kumaratilake and Antonio Ferrante and Brenton S. Robinson and Timo J{\"a}ger and Alfred Poulos},
  journal={Infection and immunity},
  year={1997},
  volume={65 10},
  pages={4152-7}
}
Effects of fatty acids on human neutrophil-mediated killing of Plasmodium falciparum asexual blood forms were investigated by using a quantitative radiometric assay. The results showed that the antiparasitic activity of neutrophils can be greatly increased (>threefold) by short-term treatment with fatty acids with 20 to 24 carbon atoms and at least three double bonds. In particular, the n-3 polyenoic fatty acids, eicosapentaenoic and docosahexaenoic acids, and the n-6 fatty acid, arachidonic… CONTINUE READING
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