Enhancement of neurite outgrowth in neuronal-like cells following boron nitride nanotube-mediated stimulation.

@article{Ciofani2010EnhancementON,
  title={Enhancement of neurite outgrowth in neuronal-like cells following boron nitride nanotube-mediated stimulation.},
  author={Gianni Ciofani and Serena Danti and Delfo D'Alessandro and Leonardo Ricotti and Stefania Moscato and Giovanni Bertoni and Andrea Falqui and Stefano Berrettini and Mario Petrini and Virgilio Mattoli and Arianna Menciassi},
  journal={ACS nano},
  year={2010},
  volume={4 10},
  pages={6267-77}
}
In this paper, we propose an absolutely innovative technique for the electrical stimulation of cells, based on piezoelectric nanoparticles. Ultrasounds are used to impart mechanical stress to boron nitride nanotubes incubated with neuronal-like PC12 cells. By virtue of their piezoelectric properties, these nanotubes can polarize and convey electrical stimuli to the cells. PC12 stimulated with the present method exhibit neurite sprout 30% greater than the control cultures after 9 days of… CONTINUE READING

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Boron Nitride Nanotubes: An Innovative Tool for Nanomedicine

  • G. Ciofani, V. Raffa, A. Menciassi, A. Cuschieri
  • Nano Today 2009,
  • 2009
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