Enhancement of intestinal adaptation by hepatocyte growth factor.

@article{Kato1998EnhancementOI,
  title={Enhancement of intestinal adaptation by hepatocyte growth factor.},
  author={Yoshifumi Kato and Dahong Yu and Marshall Z. Schwartz},
  journal={Journal of pediatric surgery},
  year={1998},
  volume={33 2},
  pages={235-9}
}
BACKGROUND/PURPOSE Hepatocyte growth factor (HGF) was originally shown to enhance hepatocyte DNA synthesis. Recently, the expression of HGF and its receptor (c-met) were observed in the intestinal tract. In a previous study, we demonstrated that HGF can increase normal rat intestinal epithelial mass and function in vivo. This study was designed to determine if HGF, given either systemically or luminally, can enhance intestinal epithelial mass and function beyond the normal adaptive response… CONTINUE READING

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