Enhancement of intestinal absorption of akebia saponin D by borneol and probenecid in situ and in vitro.
@article{Zhou2010EnhancementOI, title={Enhancement of intestinal absorption of akebia saponin D by borneol and probenecid in situ and in vitro.}, author={Yongqiang Zhou and Weize Li and Lvyi Chen and Shuwei Ma and Li Ping and Zhonglin Yang}, journal={Environmental toxicology and pharmacology}, year={2010}, volume={29 3}, pages={ 229-34 } }
58 Citations
The intestinal absorption properties of flavonoids in Hippophaë rhamnoides extracts by an in situ single-pass intestinal perfusion model
- BiologyJournal of Asian natural products research
- 2019
The results indicated that IS, QU, and KA in TFH were absorbed site-dependently, and both enterohepatic circulation and intestinal flora could participate in their absorption processes.
Absorption characteristics of the total alkaloids from Mahonia bealei in an in situ single-pass intestinal perfusion assay.
- Chemistry, BiologyChinese journal of natural medicines
- 2014
Microcrystalline preparation of akebia saponin D for its bioavailability enhancement in rats.
- Biology, Materials ScienceThe American journal of Chinese medicine
- 2015
Data suggest that the microcrystalline preparation of ASD-2 is not only reasonable in economy and suitable for large-scale preparation, but also a promising method to enhance bioavailability of ASD.
Quercetin and kaempferol increase the intestinal absorption of isorhamnetin coexisting in Elaeagnus rhamnoides (L.) A. Nelson (Elaeagnaceae) extracts via regulating multidrug resistance-associated protein 2.
- BiologyPhytomedicine : international journal of phytotherapy and phytopharmacology
- 2019
Absorption Properties of Luteolin and Apigenin in Genkwa Flos Using In Situ Single-Pass Intestinal Perfusion System in the Rat.
- BiologyThe American journal of Chinese medicine
- 2017
The study elucidated the TFG absorption mechanisms, and provided new information for its formulation preparation, and it was observed that camphor was the most effective.
The gastrointestinal behavior of saponins and its significance for their bioavailability and bioactivities
- Chemistry, Biology
- 2018
The effects of notoginsenoside R₁ on the intestinal absorption of geniposide by the everted rat gut sac model.
- Biology, ChemistryJournal of ethnopharmacology
- 2012
In Vitro and In Situ Characterization of the Intestinal Absorption of Capilliposide B and Capilliposide C from Lysimachia capillipes Hemsl
- Biology, ChemistryMolecules
- 2019
It can be concluded that the intestinal absorption mechanisms of CAPB and CAPC involve processes such as facilitated passive diffusion, efflux transporters, and enzyme-mediated metabolism.
Enhancement of oral bioavailability of akebia saponin D by destroying self-micelles and inhibiting multidrug resistance-associated protein mediated efflux
- Biology, Chemistry
- 2016
ASD-SD1 could be a promising drug delivery system to improve the oral absorption of ASD which might be by destroying self-micelles and inhibiting MRP-mediated efflux.
Intestinal absorptive transport of Genkwanin from Flos genkwa using a single-pass intestinal perfusion rat model.
- BiologyThe American journal of Chinese medicine
- 2014
The concentration-independent permeability and enhancement by coperfusion of probenecid indicated that genkwanin was transported by both passive diffusion and multidrug resistance protein (MDR)-mediated efflux mechanisms.
References
SHOWING 1-10 OF 27 REFERENCES
LC determination of cephalosporins in in vitro rat intestinal sac absorption model.
- ChemistryJournal of pharmaceutical and biomedical analysis
- 2002
In vitro permeability and metabolic stability of bile pigments and the effects of hydrophilic and lipophilic modification of biliverdin.
- BiologyBioorganic & medicinal chemistry
- 2008
Improvement of intestinal absorption of water-soluble macromolecules by various polyamines: intestinal mucosal toxicity and absorption-enhancing mechanism of spermine.
- BiologyInternational journal of pharmaceutics
- 2008
Transport characteristics of ginkgolide B by Caco-2 cells and examination of ginkgolide B oral absorption potential using rat in situ intestinal loop method.
- Biology, ChemistryInternational journal of pharmaceutics
- 2008
Complexation of tanshinone IIA with 2-hydroxypropyl-beta-cyclodextrin: effect on aqueous solubility, dissolution rate, and intestinal absorption behavior in rats.
- ChemistryInternational journal of pharmaceutics
- 2007
The enhancing effect of synthetical borneol on the absorption of tetramethylpyrazine phosphate in mouse.
- Chemistry, BiologyInternational journal of pharmaceutics
- 2007
The role of P-glycoprotein in limiting intestinal regional absorption of digoxin in rats.
- Medicine, BiologyEuropean journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
- 2001
Effects of borneol on the absorption kinetics of the rifampicin in rats' intestines
- Biology
- 2003
The results show that borneol can significantly enhance the absorption of the rifampicin in rats' intestines.
Possible Involvement of Multiple P-Glycoprotein-Mediated Efflux Systems in the Transport of Verapamil and Other Organic Cations Across Rat Intestine
- BiologyPharmaceutical Research
- 2004
The results suggest that these cationic compounds are transported by plural P-glycoprotein-mediated efflux systems with different substrate specificities depending on the intestinal site.
Intestinal absorption of novel-dipeptide prodrugs of saquinavir in rats.
- BiologyInternational journal of pharmaceutics
- 2007