Enhancement of immunity in the elderly by dietary supplementation with the probiotic Bifidobacterium lactis HN019.

@article{Gill2001EnhancementOI,
  title={Enhancement of immunity in the elderly by dietary supplementation with the probiotic Bifidobacterium lactis HN019.},
  author={Harsharnjit Singh Gill and Kay J Rutherfurd and Martin L. Cross and Pramod K. Gopal},
  journal={The American journal of clinical nutrition},
  year={2001},
  volume={74 6},
  pages={
          833-9
        }
}
BACKGROUND The aging process can lead to a decline in cellular immunity. Therefore, the elderly could benefit from safe and effective interventions that restore cellular immune functions. OBJECTIVE We determined whether dietary supplementation with the known immunostimulating probiotic Bifidobacterium lactis HN019 could enhance aspects of cellular immunity in elderly subjects. DESIGN Thirty healthy elderly volunteers (age range: 63-84 y; median: 69 y) participated in a 3-stage dietary… Expand

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The results demonstrate that dietary consumption of B. lactis HN019 can enhance natural immunity in healthy elderly subjects, and that a relatively short-term dietary regime is sufficient to impart measurable improvements in immunity that may offer significant health benefits to consumers. Expand
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Dietary consumption of the probiotic bacterium B. lactis HN019 enhanced immune function of two different types of leucocytes; the degree of enhancement was increased by consuming B. milkis in an oligosaccharide-rich substrate. Expand
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