Enhancement of hippocampally-mediated learning and protein kinase C activity by oxiracetam in learning-impaired DBA/2 mice

@article{Fordyce1995EnhancementOH,
  title={Enhancement of hippocampally-mediated learning and protein kinase C activity by oxiracetam in learning-impaired DBA/2 mice},
  author={D. Fordyce and V. J. Clark and R. Paylor and J. Wehner},
  journal={Brain Research},
  year={1995},
  volume={672},
  pages={170-176}
}
The effects of oxiracetam on hippocampally-mediated learning performance and hippocampal protein kinase C (PKC) were examined in C57BL/6Ibg (C57) and DBA/2Ibg (DBA) mice. C57 and DBA mice were subjected to daily injections of oxiracetam (50 mg/kg i.p.) or vehicle (0.9% saline) for a total of 9 days. C57 and DBA mice were examined on a modified version of the Morris water maze task and the contextual fear conditioning task on the last 5 or 2 days, respectively, of the 9-day treatment schedule… Expand
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