Enhancement of hematopoietic reconstitution with recombinant cytokines: effect of rhIL-6 in combination with rhGM-CSF and rhIL-3 on unmodified or T cell-depleted bone marrow.

Abstract

We have investigated the response of unmanipulated and lymphocyte-depleted BM cells (BMC), pretreated with monoclonal rat antihuman lymphocyte (CD52) antibody (Campath-1G) used for prevention of GvHD, to incubation with rhIL-6 alone or in combination with rhGM-CSF, rhIL-3, or both. We investigated optimal conditions needed for incubation of human BMC under… (More)

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@article{Mumcuoglu1999EnhancementOH, title={Enhancement of hematopoietic reconstitution with recombinant cytokines: effect of rhIL-6 in combination with rhGM-CSF and rhIL-3 on unmodified or T cell-depleted bone marrow.}, author={Mine Mumcuoglu and Sam Slavin}, journal={Journal of hematotherapy}, year={1999}, volume={8 3}, pages={247-53} }