Enhancement of dorsal random-pattern skin flap survival in rats with topical lidocaine and prilocaine (EMLA): enhancement of flap survival by EMLA.

@article{Karaal2005EnhancementOD,
  title={Enhancement of dorsal random-pattern skin flap survival in rats with topical lidocaine and prilocaine (EMLA): enhancement of flap survival by EMLA.},
  author={Naci Karaçal and Omer Ambarcioğlu and Umut Topal and Tagui Mamedov and Necmettin Kutlu},
  journal={The Journal of surgical research},
  year={2005},
  volume={124 1},
  pages={134-8}
}
BACKGROUND Various topical pharmacologic agents have been investigated for their efficacy in preventing or reversing skin flap ischemia. Most of these studies have focused on agents that act on the vascular smooth muscles to cause vasodilatation and improve circulation in the flap. Most of local anesthetics relax vascular smooth muscle and produce… CONTINUE READING