Enhancement of collagen-induced arthritis in female mice by estrogen receptor blockage.

Abstract

OBJECTIVE To determine whether estrogen-mediated suppression of collagen-induced arthritis (CIA) in mice acts via the nuclear estrogen receptors (ERs). METHODS CIA was induced in noncastrated normal (B10.Q x DBA/1)F1 (QD) female mice. The mice were treated with the ER antagonist ICI 182,780, which binds to both ERalpha and ERbeta, either on days 2, 6, 10… (More)

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Cite this paper

@article{Jansson2001EnhancementOC, title={Enhancement of collagen-induced arthritis in female mice by estrogen receptor blockage.}, author={Lauren M. Jansson and Richard Holmdahl}, journal={Arthritis and rheumatism}, year={2001}, volume={44 9}, pages={2168-75} }