Enhancement of cellulosome-mediated deconstruction of cellulose by improving enzyme thermostability

Abstract

BACKGROUND The concerted action of three complementary cellulases from Clostridium thermocellum, engineered to be stable at elevated temperatures, was examined on a cellulosic substrate and compared to that of the wild-type enzymes. Exoglucanase Cel48S and endoglucanase Cel8A, both key elements of the natural cellulosome from this bacterium, were engineered… (More)
DOI: 10.1186/s13068-016-0577-z

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Cite this paper

@inproceedings{Moras2016EnhancementOC, title={Enhancement of cellulosome-mediated deconstruction of cellulose by improving enzyme thermostability}, author={Sarah Mora{\"i}s and Johanna Stern and Amaranta Kahn and Anastasia P. Galanopoulou and Shahar Yoav and Melina Shamshoum and Matthew A. Smith and Dimitris G. Hatzinikolaou and Frances H. Arnold and Edward A Bayer}, booktitle={Biotechnology for biofuels}, year={2016} }