Enhancement of aquaporin-3 by vasoactive intestinal polypeptide in a human colonic epithelial cell line.

@article{Itoh2003EnhancementOA,
  title={Enhancement of aquaporin-3 by vasoactive intestinal polypeptide in a human colonic epithelial cell line.},
  author={Akihiko Itoh and Tomoyuki Tsujikawa and Yoshihide Fujiyama and Tadao Bamba},
  journal={Journal of gastroenterology and hepatology},
  year={2003},
  volume={18 2},
  pages={203-10}
}
BACKGROUND Vasoactive intestinal polypeptide (VIP) plays an important role in water transport in the intestine. Several specialized channels termed aquaporins (AQP) facilitate water transport in the gastrointestinal tract. Aquaporin-3 localizes to epithelial cells in the human small intestine and colon. However, the regulatory mechanisms underlying the functions of AQP3 remain unclear. To characterize the regulation of AQP3 expression by VIP, we studied messenger (m)RNA expression, protein… CONTINUE READING

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