Enhancement of apoptosis by sonodynamic therapy with protoporphyrin IX in isolate sarcoma 180 cells.

@article{Wang2008EnhancementOA,
  title={Enhancement of apoptosis by sonodynamic therapy with protoporphyrin IX in isolate sarcoma 180 cells.},
  author={Xiao bing Wang and Quan Liu and Pu Patrick Wang and Kun Zhang and Wei Tang and Bao Lu Wang},
  journal={Cancer biotherapy & radiopharmaceuticals},
  year={2008},
  volume={23 2},
  pages={
          238-46
        }
}
This study was to investigate whether the apoptosis in isolate sarcoma 180 (S180) cells could be enhanced by ultrasound in the presence of protoporphyrin IX (PPIX) and also to evaluate the underlying biologic mechanism. S180 cells were exposed to ultrasound for 30 seconds' duration, at the frequency of 2.2 MHz and an acoustical power of 3 W/cm(2) with 120 microM of PPIX. Cell apoptosis was evaluated based on the morphologic changes at different incubation times after sonication. Our results… CONTINUE READING
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