Enhancement of antibiotic elution from acrylic bone cement.

  title={Enhancement of antibiotic elution from acrylic bone cement.},
  author={Konstantinos Anagnostakos and Jens Kelm},
  journal={Journal of biomedical materials research. Part B, Applied biomaterials},
  volume={90 1},
Antibiotic-loaded acrylic bone cement is a well-established tool in the prophylaxis and treatment of orthopedic infections. Numerous studies about its pharmacokinetic properties have demonstrated that only a small part of the incorporated antibiotic amounts can be released, mostly over the first 8-10 weeks. Therefore, in the past 10 years, several attempts have been made for enhancement of the drug elution from bone cement. This article reviews this experience and pays special attention on… CONTINUE READING

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