Enhancement of angiogenesis by the implantation of self bone marrow cells in a rat ischemic heart model.

@article{Kobayashi2000EnhancementOA,
  title={Enhancement of angiogenesis by the implantation of self bone marrow cells in a rat ischemic heart model.},
  author={T. Kobayashi and Kimikazu Hamano and T S Li and Tomoe Katoh and S. Kobayashi and Michio Matsuzaki and Kensuke Esato},
  journal={The Journal of surgical research},
  year={2000},
  volume={89 2},
  pages={
          189-95
        }
}
Background. Bone marrow contains various kinds of primitive cells which differentiate into endothelial cells and could secrete several growth factors. Therefore, we attempted to induce therapeutic angiogenesis using self bone marrow cells in a rat model. Materials and methods. Quantitative angiogenesis was examined using a sponge implantation assay that indicated whether the rat bone marrow cells had induced angiogenesis or not. Employing a rat ischemic heart model, bone marrow cells were… 
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