Enhancement of amlodipine cardioprotection by quercetin in ischaemia/reperfusion injury in rats.

@article{Ahmed2009EnhancementOA,
  title={Enhancement of amlodipine cardioprotection by quercetin in ischaemia/reperfusion injury in rats.},
  author={Lamiaa A. Ahmed and Hesham Salem and Amina Salem Attia and Mostafa E. El-sayed},
  journal={The Journal of pharmacy and pharmacology},
  year={2009},
  volume={61 9},
  pages={
          1233-41
        }
}
OBJECTIVES To investigate the possible modification of the cardioprotective effect of amlodipine when co-administered with quercetin in myocardial ischaemia/reperfusion-induced functional, metabolic and cellular alterations in rats. METHODS Oral doses of amlodipine (15 mg/kg) and quercetin (5 mg/kg), alone or in combination, were administered once daily for 1 week. Rats were then subjected to myocardial ischaemia/reperfusion (35(min)/10(min)). Heart rates and ventricular arrhythmias were… 
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