Enhancement of acoustic evoked potentials and impairment of startle reflex induced by reduction of GABAergic control of the neural substrates of aversion in the inferior colliculus.

@article{Nobre2003EnhancementOA,
  title={Enhancement of acoustic evoked potentials and impairment of startle reflex induced by reduction of GABAergic control of the neural substrates of aversion in the inferior colliculus.},
  author={Manoel Jorge Nobre and Guy Sandner and Marcus Lira Brand{\~a}o},
  journal={Hearing research},
  year={2003},
  volume={184 1-2},
  pages={82-90}
}
The neural network of the inferior colliculus (IC), implicated in the generation of defensive behavior to aversive acoustic stimuli, is under tonic GABAergic control. Dopamine also seems to have a modulatory role in these neural circuits. It is still unclear how such changes in transmission of acoustic information influence the motor expression of the defensive behavior. Startle reaction to a sudden noise has been used as an effective way to measure the motor reactivity of rats to fearful… CONTINUE READING
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