Enhancement of Metallosphaera sedula Bioleaching by Targeted Recombination and Adaptive Laboratory Evolution.

@article{McCarthy2018EnhancementOM,
  title={Enhancement of Metallosphaera sedula Bioleaching by Targeted Recombination and Adaptive Laboratory Evolution.},
  author={Samuel McCarthy and Chenbing Ai and P. Blum},
  journal={Advances in applied microbiology},
  year={2018},
  volume={104},
  pages={
          135-165
        }
}
  • Samuel McCarthy, Chenbing Ai, P. Blum
  • Published 2018
  • Biology, Medicine
  • Advances in applied microbiology
  • Thermophilic and lithoautotrophic archaea such as Metallosphaera sedula occupy acidic, metal-rich environments and are used in biomining processes. Biotechnological approaches could accelerate these processes and improve metal recovery by biomining organisms, but systems for genetic manipulation in these organisms are currently lacking. To gain a better understanding of the interplay between metal resistance, autotrophy, and lithotrophic metabolism, a genetic system was developed for M. sedula… CONTINUE READING
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