Enhancement of Insulin Transport Across Primary Rat Alveolar Epithelial Cell Monolayers by Endogenous Cellular Factor(s)

@article{Bahhady2007EnhancementOI,
  title={Enhancement of Insulin Transport Across Primary Rat Alveolar Epithelial Cell Monolayers by Endogenous Cellular Factor(s)},
  author={Rana Bahhady and Kwang-Jin Kim and Zea Borok and Edward D Crandall and Wei-Chiang Shen},
  journal={Pharmaceutical Research},
  year={2007},
  volume={24},
  pages={1713-1719}
}
To characterize factor(s) contained in apical medium of primary cultured rat alveolar epithelial type II cell-like monolayers (RAECM-II) that enhance insulin absorption across alveolar epithelial cells. Primary rat alveolar epithelial cell monolayers cultured on Transwells in the presence and absence of 10 ng/ml keratinocyte growth factor for 6 days were dosed from the apical compartment with radiolabeled insulin in: newborn bovine serum-containing medium (SM), conditioned medium from apical… CONTINUE READING
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