Enhancement of Glucantime therapy of murine Leishmania donovani infection by a synthetic immunopotentiating compound (CP-46,665-1).

@article{Adinolfi1985EnhancementOG,
  title={Enhancement of Glucantime therapy of murine Leishmania donovani infection by a synthetic immunopotentiating compound (CP-46,665-1).},
  author={Luigi Elio Adinolfi and Peter F. Bonventre},
  journal={The American journal of tropical medicine and hygiene},
  year={1985},
  volume={34 2},
  pages={270-7}
}
The therapeutic efficacy of CP-46,665-1, a synthetic lipoidal amine with proven immunomodulatory and anti-tumor properties, in combination with chemotherapy was evaluated in L. donovani-infected C57Bl/6 mice. Immunostimulation and drug treatment resulted in a 10-fold lesser infection level than in untreated mice, while animals treated with Glucantime alone… CONTINUE READING